Important Safety Information

Important Safety Information

Important Safety Information for Wegovy (semaglutide) injection

Warning: Risk of Thyroid C-Cell Tumors


In studies with mice and rats, semaglutide (the active ingredient in Wegovy and Ozempic) caused thyroid tumors, including thyroid cancer. It is not known if Wegovy will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people. 


⚠ Tell your provider if you notice:


  • A lump or swelling in your neck
  • Hoarseness
  • Trouble swallowing
  • Shortness of breath 


These may be symptoms of thyroid cancer.


Do not use Wegovy if you or your family have ever had medullary thyroid carcinoma (MTC) or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2).

What is Wegovy used for? 


Wegovy is a glucagon-like peptide-1 (GLP-1) receptor agonist used for chronic weight management in people with a body mass index (BMI) of: 


  • 30 kg/m² or greater (obesity)
  • 27 kg/m² or greater (overweight) with at least one weight-related condition (e.g., high blood pressure, type 2 diabetes, high cholesterol)

Who Should NOT Use Wegovy?


Do not use Wegovy if: 


❌ You or your family have ever had medullary thyroid carcinoma (MTC) 

❌ You have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

❌ You have a known allergic reaction to semaglutide


How is Wegovy Administered?


  • Take once a week, on the same day each week
  • Inject subcutaneously (under the skin) in the stomach, thigh, or upper arm
  • Can be taken with or without food

⚠ Do not change your dose or stop taking Wegovy without consulting your provider. 

What Should I Tell My Provider Before Using Wegovy? 


Wegovy can interact with other medications, including: 

  • Diabetes medications (e.g., insulin, sulfonylureas)
  • Other GLP-1 receptor agonists (e.g., Ozempic, Saxenda, Victoza, Byetta, Bydureon) 
  • Medications that delay gastric emptying 


Tell your Aspire Medical Group provider if you have a history of:


✔ Thyroid cancer

✔ Pancreatitis

✔ Kidney disease

✔ Diabetic retinopathy

✔ Depression or suicidal thoughts


⚠ If you are pregnant or planning pregnancy: 


  • Do not use Wegovy during pregnancy 
  • Stop taking Wegovy at least 2 months before trying to conceive 


📞 Pregnancy Registry: Contact Novo Nordisk at 1-800-727-6500 if you are pregnant and have taken Wegovy.


Serious Side Effects of Wegovy


🚨 Seek immediate medical help if you experience: 


  • Thyroid tumors or symptoms of thyroid cancer
  • Pancreatitis (severe stomach pain, nausea, vomiting) 
  • Gallbladder disease (stomach pain, yellowing of the skin, fever) 
  • Kidney problems (dehydration, changes in urination) 
  • Severe allergic reactions (swelling, rash, breathing problems)
  • Low blood sugar (dizziness, blurred vision, sweating, fast heartbeat) 
  • Vision changes if you have diabetes 
  • Mental health changes, including suicidal thoughts 


Common Side Effects of Wegovy 


  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Headache
  • Fatigue


📞 Report side effects: Contact Novo Nordisk at 1-833-934-6891 or FDA MedWatch at 1-800-FDA-1088


🔗 Full Prescribing Information: Wegovy PI 

Important Safety Information for Ozempic (semaglutide) injection 

Warning: Risk of Thyroid C-Cell Tumors 


(Same warnings as Wegovy regarding thyroid tumors and medullary thyroid carcinoma)


What is Ozempic used for?


Ozempic is a GLP-1 receptor agonist used to:


✔ Improve blood sugar control in type 2 diabetes (with diet & exercise)

✔ Reduce the risk of heart attack and stroke in people with type 2 diabetes and heart disease


❌ Not for type 1 diabetes


Who Should NOT Use Ozempic? 


Same contraindications as Wegovy.


📞 Report side effects: Contact Novo Nordisk at 1-833-934-6891 or FDA MedWatch at 1-800-FDA-1088


🔗 Full Prescribing Information: Ozempic PI

Important Safety Information for Zepbound (tirzepatide) injection

Warning: Risk of Thyroid C-Cell Tumors


Zepbound is used for weight management in adults with:


✔ Obesity (BMI 30+ kg/m²)

✔ Overweight (BMI 27+ kg/m²) with a related condition


❌ Not for use with other GLP-1 receptor agonists or weight loss medications


📞 Report side effects: Contact Eli Lilly at 1-800-LillyRx (1-800-545-5979) or FDA MedWatch at 1-800-FDA-1088


🔗 Full Prescribing Information: Zepbound PI

Important Safety Information for Compounded Semaglutide Injection

⚠ Compounded semaglutide is not FDA-approved and has not undergone full safety review.


📞 Report side effects: Contact FDA MedWatch at 1-800-FDA-1088


🔗 Full Consumer Medical Information: Available upon request. 

Have Questions? Contact Aspire Medical Group!

📍 Aspire Medical Group PC, DBA Aspire Medical Group 



📞 Call: (617)-991-9151


📧 Email: info@aspiremedgroup.com

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